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PT-141 10mg
PT-141 10mg
PT-141 10mg
PT-141 10mg
PT-141 10mg
PT-141 10mg
PT-141 10mg

PT-141 10mg

£16.99

  • OP Labs formerly Oxford Peptides
  • Batch tested Purity: ≥ 98.5 % (HPLC, typical)
  • CAS Number: 42464-96-0
  • Molecular Formula: C₁₀H₁₁N₂⁺
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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies are performed outside of the body. These products are not medicines or drugs and have not been approved to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden.

Description

Description & Mechanism

PT-141 is a synthetic cyclic heptapeptide derived from melanocortin peptides and developed for experimental investigation of melanocortin receptor–mediated signalling pathways. It is structurally related to Melanotan II but exhibits distinct receptor selectivity and signalling characteristics.

In biochemical and cellular research systems, PT-141 interacts primarily with melanocortin receptors (MC1R, MC3R, MC4R), initiating intracellular signalling cascades associated with cAMP production and downstream transcriptional regulation. Experimental studies investigate receptor binding affinity, signalling bias, and comparative behaviour relative to other melanocortin analogues. Observed molecular responses depend on concentration, exposure duration, and experimental model.

Applications in Research

  • As a molecular probe for studying melanocortin receptor signalling
  • Investigation of GPCR-mediated intracellular signalling pathways
  • In vitro studies examining receptor selectivity and peptide stability
  • Use as a reference compound in neuroendocrine and peptide signalling research

Specifications Summary

Purity (HPLC): ≥ 99 %
Appearance: White to off-white lyophilised powder
Molecular Weight: ~1025.18 g/mol
Peptide Type: Synthetic melanocortin analogue
Solubility: Water, buffered aqueous solutions
Storage: –20 °C, desiccated, protected from light
Pack Size: 10 mg

Handling, Reconstitution & Stability

  • Weigh under dry conditions; peptide is hygroscopic
  • Reconstitute in sterile water or appropriate buffered aqueous solution
  • Avoid vigorous agitation during dissolution
  • Filter sterilize if required prior to use
  • Aliquot and store reconstituted solutions at –20 °C or lower
  • Avoid repeated freeze–thaw cycles

Precautions & Notes

  • Experimental behaviour is influenced by receptor expression, peptide concentration, and exposure duration
  • Buffer composition, pH, and ionic strength may affect peptide stability
  • Appropriate controls are recommended to distinguish receptor-specific effects
  • Intended strictly for laboratory research use

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