BPC-157 5mg

Description

Description & Mechanism

BPC-157 is a synthetic oligopeptide consisting of fifteen amino acids, corresponding to a defined sequence originally identified within a larger gastric-derived protein. In research contexts, it is studied as a discrete pentadecapeptide with reproducible physicochemical properties, allowing its use in biochemical, cellular, and preclinical experimental systems.

In biochemical and cellular research models, BPC-157 has been reported to interact with multiple signalling pathways, including nitric oxide–associated mechanisms, growth factor-related signalling, and cytoskeletal regulatory processes. Observed molecular and cellular responses are highly dependent on experimental conditions, concentration, exposure duration, and model system. As such, BPC-157 is utilised as a molecular probe for investigating peptide-mediated signalling behaviour rather than defined biological or physiological outcomes.

Applications in Research

• As a molecular tool to study short peptide–mediated signalling pathways
• Investigation of intracellular signalling networks involving nitric oxide–associated and growth factor-related pathways
• In vitro studies examining cytoskeletal organisation and cell–matrix interaction dynamics
• Preclinical or ex vivo experimental models for mechanistic investigation of oligopeptide signalling

Specifications Summary

Handling, Reconstitution & Stability

• Weigh under dry conditions; peptide is hygroscopic
• Reconstitute in sterile water or appropriate buffered aqueous solution depending on assay requirements
• Avoid vigorous agitation during dissolution
• Filter sterilize if required (e.g. 0.22 µm) prior to use
• Aliquot and store reconstituted solutions at –20 °C or below to minimise degradation
• Avoid repeated freeze–thaw cycles

Precautions & Notes

• Experimental behaviour of BPC-157 is dependent on concentration, model system, and exposure conditions
• Due to reported interaction with multiple signalling pathways, appropriate experimental controls are recommended
• Prolonged exposure to light, elevated temperature, or aqueous environments may reduce stability
• As of 2022, BPC-157 (PL-14736) is listed by the World Anti-Doping Agency (WADA) under the S0 category of prohibited substances; this designation is unrelated to research use
• Intended strictly for laboratory research use; not for human or veterinary application