NAD+ 10ml

Description

Description & Mechanism

Nicotinamide adenine dinucleotide (NAD+) is an endogenous pyridine nucleotide that functions as a central redox cofactor and signalling molecule in cellular metabolism. In its oxidised form, NAD+ participates in electron transfer reactions fundamental to oxidative phosphorylation, glycolysis, and mitochondrial energy production.

In biochemical and cellular research systems, NAD+ is extensively studied for its role in redox balance, substrate availability for NAD+-dependent enzymes, and regulation of intracellular signalling pathways. These include sirtuins, poly(ADP-ribose) polymerases (PARPs), and cyclic ADP-ribose–generating enzymes involved in DNA repair, chromatin regulation, and calcium signalling. Experimental outcomes are influenced by intracellular NAD+/NADH ratios, compartmentalisation, and metabolic state of the model system.

Applications in Research

• Investigation of cellular redox metabolism and mitochondrial function
• Studies of NAD+-dependent enzymes including sirtuins and PARPs
• In vitro research on energy homeostasis and metabolic signalling pathways
• Use as a reference compound in enzymology and metabolic research

Handling & Stability

• Store in a cool dark place. Discard 30 DAYS after opening.
• Shelf life: 30 MONTHS from production

Specifications Summary

Purity: 100mg/ml
Appearance: Clear liquid
Chemical Type: Pyridine nucleotide coenzyme
Molecular Weight: ~663.43 g/mol
Storage: Store in a cool dark place. Discard 30 DAYS after opening.
Pack Size: 10ml

Precautions & Notes

• Experimental behaviour of NAD+ is influenced by pH, temperature, and redox environment.
• NAD+ is sensitive to hydrolysis under acidic or basic conditions.
• Appropriate controls are recommended when interpreting enzyme-dependent effects.
• Intended strictly for laboratory research use only; not for human or veterinary application.