Description
Description & Mechanism
Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide tuftsin, modified to enhance stability and suitability for experimental investigation. It has been developed as a research tool for studying neuropeptide signalling, neuroimmune interactions, and central nervous system regulatory pathways.
In biochemical and cellular research systems, Selank has been examined for its influence on neuronal signalling pathways, including modulation of neurotransmitter systems and stress-response–associated signalling cascades. Experimental models often investigate its effects on gene expression, neuroimmune communication, and peptide–receptor interactions. Observed molecular responses are dependent on experimental design, concentration, and model system.
Applications in Research
- As a molecular probe for studying neuropeptide-mediated signalling pathways.
- Investigation of neuroimmune interactions and CNS regulatory mechanisms.
- In vitro and in vivo studies examining peptide stability and signalling behaviour.
- Use as a reference compound in neurobiology and peptide signalling research.
Specifications Summary
Purity (HPLC): ≥ 99 %
Appearance: White to off-white lyophilised powder
Molecular Weight: ~751.9 g/mol
Peptide Type: Synthetic neuropeptide
Solubility: Water, buffered aqueous solutions
Storage: –20 °C, desiccated, protected from light
Pack Size: 5 mg
Handling, Reconstitution & Stability
- Weigh under dry conditions; peptide is hygroscopic.
- Reconstitute in sterile water or appropriate buffered aqueous solution.
- Avoid vigorous agitation during dissolution.
- Filter sterilize if required prior to use.
- Aliquot and store reconstituted solutions at –20 °C or lower.
- Avoid repeated freeze–thaw cycles.
Precautions & Notes
- Experimental behaviour of Selank is influenced by neuronal model, receptor expression, peptide concentration, and exposure duration.
- Buffer composition, pH, and ionic strength may affect peptide stability.
- Appropriate controls are recommended.
- Intended strictly for laboratory research use.










